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Patterns in transcription factor binding help predict whether undifferentiated cells

Decoding how cells choose to become muscles or neurons

FMI researchers have uncovered new clues about how cells decide what type of cell to become — whether muscle, neurons, or something else entirely. By studying proteins called transcription factors, they identified patterns that predict…

© IOB, 2025

The eye’s secret clockwork

Perception depends not only on what we see, but also on when we see it. Signals initiated by light-sensitive cells in the retina travel through nerve fibers of varying lengths before converging at the optic nerve and continuing to the…

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Invitation to participate in a Survey: Exploring a Swiss EBRAINS National Node: Deadline: 31 August 2025

The EBRAINS Swiss National Node Task Force group invites you to take part in a short national survey and give your input on an important initiative concerning the future of neuroscience research as part of a wide-ranging and consolidated…

Professor Ludwig Kappos

Professor Ludwig Kappos wins the prestigious MS Charcot Award

Professor Ludwig Kappos, Director of Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), has been awarded the 2025 Charcot Award by the MS International Federation (MSIF)! This prestigious lifetime achievement award…

Researchers uncovered how the brain balances excitatory and inhibitory neurons to organize and process memories.

How brain networks balance learning and memory

FMI researchers have provided new insights into how the brain organizes and processes memories, thanks to a study that looks at the balance between excitatory and inhibitory neurons. Memory networks have been thought to rely on stable…

SNr neurons in the midbrain send precise signals to control movement. Their activity determines which movements actions are initiated or inhibited. (Image: Biozentrum, University of Basel)

A switchboard with precision: How the brain licenses movements

Neurons deep in the brain not only help to initiate movement—they also actively suppress it, and with astonishing precision. This is the conclusion of a new study by researchers at the University of Basel and the Friedrich Miescher…

FMI researchers adapted a mouse experiment

How the brain detects surprises — and why it could matter for mental health

What happens in the brain when our senses don’t match our expectations — for example, when we take a step, but there’s no sound or the sound is delayed or distorted? A new study led by FMI neuroscientists sheds light on how the brain…

Sections of multinucleated muscle fibers (green; nuclei in magenta).

New insights challenge previous views about a muscle growth factor

The protein Myc has long been thought to support skeletal muscle growth. In recent work, the research team led by Prof. Markus Rüegg at the Biozentrum, University of Basel, provides compelling evidence that Myc in muscle fibers is…

Junger Basler Nachwuchswissenschaftler mit Hirnliga-Forschungsstipendium ausgezeichnet

Junger Basler Nachwuchswissenschaftler mit Hirnliga-Forschungsstipendium ausgezeichnet

Das Forschungsstipendium 2025 über 60’000 Franken der Schweizerischen Hirnliga geht an den erst 22-jährigen Valiantsin Darafeyeu, PhD-Student in der Forschungsgruppe von Prof. Dr. Andreas Keller (Departement für Biomedizin der Universität…

Image © IOB, 2025

Brain's efficiency emerges from randomness

Scientists have wondered for a long time how neurons in our brain process information so efficiently. Traditional theories suggested that this required precisely tuned neural patterns. However, new research at IOB shows that highly…

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