Decoding how cells choose to become muscles or neurons

Patterns in transcription factor binding help predict whether undifferentiated cells

Patterns in transcription factor binding help predict whether undifferentiated cells (center) become neurons (left) or muscle cells (right). Image credit: Sevi Durdu/FMI

FMI researchers have uncovered new clues about how cells decide what type of cell to become — whether muscle, neurons, or something else entirely. By studying proteins called transcription factors, they identified patterns that predict where these proteins bind on DNA and how they influence a cell’s fate. The findings could help scientists better understand development and disease. More

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